Preheat the oven to 400°F (200°C). Line a large baking sheet with parchment paper.
In a large bowl, whisk together the flour, granulated sugar, baking powder, salt, cinnamon, and orange zest.
Add the cold cubed butter. Cut it into the dry ingredients using a pastry cutter or your fingertips until the mixture resembles coarse crumbs with a few pea-sized butter pieces.
Stir in the dried cranberries.
In a separate bowl, whisk the egg, ¾ cup cold heavy cream, and 1 teaspoon vanilla extract.
Pour the wet ingredients into the dry ingredients. Fold gently just until a shaggy dough begins to form.
Turn the dough onto a lightly floured surface. Gently bring it together and fold it over itself 2–3 times. Do not overmix.
Pat the dough into an 8-inch circle about 1 inch thick. Cut into 8 equal wedges.
Place the scones on the prepared baking sheet, spacing them about 2 inches apart. Brush the tops with 1 tablespoon heavy cream and sprinkle with coarse sugar, if using.
Chill the shaped scones for 10–15 minutes if the dough feels warm.
Bake for 18–20 minutes, until golden on top and cooked through. Cool on the baking sheet for 5 minutes, then transfer to a wire rack.
For the glaze, whisk the powdered sugar, 1–2 tablespoons orange juice, and ½ teaspoon vanilla extract until smooth. Drizzle over slightly cooled scones and let set for 10 minutes before serving.